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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIAH2
All Species:
30.3
Human Site:
S282
Identified Species:
55.56
UniProt:
O43255
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43255
NP_005058.3
324
34615
S282
T
W
E
A
T
P
R
S
I
H
D
G
V
A
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_863586
282
31108
I243
W
E
A
T
P
R
S
I
H
E
G
I
A
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q06986
325
34739
S283
T
W
E
A
T
P
R
S
I
H
D
G
V
A
A
Rat
Rattus norvegicus
Q8R4T2
325
34681
S283
T
W
E
A
T
P
R
S
I
H
D
G
V
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507643
433
47638
S393
T
W
E
A
T
P
R
S
I
H
E
G
I
A
T
Chicken
Gallus gallus
XP_426719
319
34023
S277
T
W
E
A
T
P
R
S
I
H
D
G
V
N
A
Frog
Xenopus laevis
Q9I8X5
313
34081
H273
E
A
T
P
R
S
I
H
D
G
V
A
A
A
I
Zebra Danio
Brachydanio rerio
Q7SYL3
331
34475
S291
T
W
E
A
T
P
R
S
I
H
D
G
V
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P21461
314
33689
S274
T
W
E
A
M
P
R
S
I
H
E
G
V
A
S
Honey Bee
Apis mellifera
XP_394284
279
30558
I240
W
E
A
M
P
R
S
I
H
E
G
V
S
S
A
Nematode Worm
Caenorhab. elegans
Q965X6
339
37641
S294
S
W
E
A
T
P
R
S
I
H
E
G
V
V
V
Sea Urchin
Strong. purpuratus
XP_797311
281
31248
I242
W
E
A
T
P
R
S
I
H
E
G
V
Q
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9STN8
327
36556
I283
R
D
S
N
D
G
L
I
I
Q
R
N
M
A
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
70.6
N.A.
97.8
98.1
N.A.
56.5
91
85.8
76.1
N.A.
66.3
67.9
54.8
66.9
Protein Similarity:
100
N.A.
N.A.
78.4
N.A.
97.8
98.1
N.A.
63.9
93.5
88.2
82.4
N.A.
76.8
76.8
66.9
76.2
P-Site Identity:
100
N.A.
N.A.
6.6
N.A.
100
100
N.A.
80
93.3
6.6
100
N.A.
80
6.6
73.3
13.3
P-Site Similarity:
100
N.A.
N.A.
6.6
N.A.
100
100
N.A.
93.3
93.3
6.6
100
N.A.
93.3
13.3
86.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
24
62
0
0
0
0
0
0
0
8
16
70
62
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
8
0
0
0
8
0
39
0
0
0
0
% D
% Glu:
8
24
62
0
0
0
0
0
0
24
24
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
0
0
8
24
62
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
24
62
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
31
70
0
0
8
8
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% L
% Met:
0
0
0
8
8
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
8
0
8
0
% N
% Pro:
0
0
0
8
24
62
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% Q
% Arg:
8
0
0
0
8
24
62
0
0
0
8
0
0
0
0
% R
% Ser:
8
0
8
0
0
8
24
62
0
0
0
0
8
8
8
% S
% Thr:
54
0
8
16
54
0
0
0
0
0
0
0
0
8
8
% T
% Val:
0
0
0
0
0
0
0
0
0
0
8
16
54
8
8
% V
% Trp:
24
62
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _